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A keloid scar is basically the only time I think of collagen as a bad thing, because too much of it following an injury or a mole removal procedure, (in my case), can actually cause a scar that is raised and larger than the initial injury, which can also be itchy and painful.
According to J. Peter Rubin, MD, Chair of the University of Pittsburgh’s Department of Plastic Surgery, fat transfer is a minimally invasive technique in which fat is removed from what part of the body with liposuction methods, and the fat is processed to prepare it for grafting, and then the fat is injected into another part of the body.
People have long speculated on what causes unsightly varicose veins, with some believing that crossing your legs when you sit for extended periods of time is the culprit. As the Mayo Clinic notes, while that may be one factor, there are other causes for these as well.